Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

6 questions · 11 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 11 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Sodium fluoride (5% NaF, one-time [Mauro] or every 6 months [Liu]) vs Control (water or unspecified)

New coronal caries in permanent molars (caries prevention) · Children with dental caries in permanent (first) molars

NaF gave a 48% prevented fraction (fissure site) vs water (p<0.002; ungraded).

3 findings from 1 review

Resin sealant (one-time) vs Control (water)

New coronal caries in permanent molars (caries prevention) · Children with dental caries in permanent (first) molars

Resin sealant gave a 65% prevented fraction (fissure site) vs water, the highest fissure-site value (p<0.002; ungraded).

2 findings from 1 review

Atraumatic restorative treatment (ART) sealant (one-time) vs no treatment

New coronal caries in permanent first molars (caries prevention) · Children with dental caries in permanent (first) molars

ART within a brushing programme significantly reduced caries vs control (p<0.01; ungraded).

2 findings from 1 review

2.26% ammonium bifluoride (one-time) vs Control (details reported as unavailable)

New coronal caries in permanent first molars (caries prevention) · Children with dental caries in permanent (first) molars

One-time ammonium bifluoride gave a 56% prevented fraction, similar to SDF (57%) (single study; ungraded).

1 finding from 1 review

38% SDF (one-time application) vs inactive control

New coronal carious lesions or fillings on permanent (first) molars (caries prevention) · Children with dental caries in permanent (first) molars

One-time SDF within a brushing programme did not significantly reduce caries vs control (p>0.05; ungraded).

2 findings from 1 review

38% SDF (one-time application) vs Information unavailable

New coronal carious lesions or fillings on permanent (first) molars (caries prevention) · Children with dental caries in permanent (first) molars

One-time 38% SDF gave a 57% prevented fraction for caries in children's permanent first molars (single study; ungraded).

1 finding from 1 review