Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews · Pregnancy and Childbirth

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 33.3%Low 2 · 66.7%Moderate 0 · 0%High 0 · 0%

Oral anti‐diabetic pharmacological therapies vs placebo (outcomes

Neonatal hypoglycaemia · Infants of women diagnosed with gestational diabetes

It is very uncertain whether oral anti‐diabetic pharmacological therapies changes neonatal hypoglycaemia compared with placebo ‐ neonatal outcomes (very low certainty).

1 finding from 1 review

Oral anti‐diabetic pharmacological therapies for the treatment of women with gestational diabetes 2017 · Cochrane Headline outcomes only
RR 1.97 [0.36, 10.62]
1 study · 375 participants
Very low

Metformin vs glibenclamide ‐ neonatal outcomes

Neonatal hypoglycaemia · Infants of women diagnosed with gestational diabetes

Metformin showed no clear difference in neonatal hypoglycaemia compared with glibenclamide ‐ neonatal outcomes (low certainty).

1 finding from 1 review

Oral anti‐diabetic pharmacological therapies for the treatment of women with gestational diabetes 2017 · Cochrane Headline outcomes only
RR 0.86 [0.42, 1.77]
4 studies · 554 participants
Low

Glibenclamide vs acarbose ‐ neonatal outcomes

Neonatal hypoglycaemia · women with gestational diabetes mellitus

Glibenclamide showed no clear difference in neonatal hypoglycaemia compared with acarbose ‐ neonatal outcomes (low certainty).

1 finding from 1 review

Oral anti‐diabetic pharmacological therapies for the treatment of women with gestational diabetes 2017 · Cochrane Headline outcomes only
RR 6.33 [0.87, 46.32]
1 study · 43 participants
Low