What do systematic reviews say?

NSAIDs vs placebo

It is very uncertain whether NSAID changes need for blood transfusion compared with placebo (very low certainty).

• Perioperative systemic nonsteroidal anti‐inflammatory drugs (NSAIDs) in women undergoing breast surgery 2021 · Cochrane Headline outcomes only
  RR 4.62 [0.23, 91.34]
  1 study · 48 participants
  Very low