Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Neonatal

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 2 · 100%High 0 · 0%

HFNC vs nasal intermittent positive pressure ventilation

Nasal trauma (during assigned treatment) · preterm infants requiring primary respiratory support

Nasal high flow probably leads to lower nasal trauma (during assigned treatment) compared with nasal intermittent positive pressure ventilation (moderate certainty).

1 finding from 1 review

Nasal high flow therapy for primary respiratory support in preterm infants 2023 · Cochrane Headline outcomes only
RR 0.21 [0.09, 0.47]
3 studies · 272 participants
Moderate

HFNC vs continuous positive airway pressure (CPAP)

Nasal trauma (during assigned treatment) · preterm infants requiring primary respiratory support

Nasal high flow probably leads to lower nasal trauma (during assigned treatment) compared with continuous positive airway pressure (moderate certainty).

1 finding from 1 review

Nasal high flow therapy for primary respiratory support in preterm infants 2023 · Cochrane Headline outcomes only
RR 0.49 [0.36, 0.68]
7 studies · 1595 participants
Moderate