What do systematic reviews say?

Gradient technique vs wash and centrifugation

It is very uncertain whether gradient technique changes multiple pregnancy rate per couple compared with wash and centrifugation (very low certainty).

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  OR 0.33 [0.01, 8.83]
  1 study · 31 participants
  Very low

Swim‐up technique vs gradient technique

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 25 participants
  Very low

Swim‐up technique vs wash and centrifugation

It is very uncertain whether swim‐up technique changes multiple pregnancy rate per couple compared with wash and centrifugation (very low certainty).

• Semen preparation techniques for intrauterine insemination 2019 · Cochrane Headline outcomes only
  OR 0.49 [0.02, 13.28]
  1 study · 26 participants
  Very low