Findings

What do systematic reviews say?

4 questions · 4 findings · 2 reviews

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No studies found 2 · 50%GRADE not reported 0 · 0%Very low 1 · 25%Low 1 · 25%Moderate 0 · 0%High 0 · 0%

GnRH agonists vs GnRH antagonists

Multiple pregnancy rate · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes

GnRH agonists showed no clear difference in multiple pregnancy rate compared with gnRH antagonists (low certainty).

1 finding from 1 review

Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes 2020 · Cochrane Headline outcomes only
OR 0.69 [0.45, 1.07]
1 study · 473 participants
Low

GnRH agonists vs control

Multiple pregnancy rate · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes

The review found no eligible studies for this question.

1 finding from 1 review

Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

GnRH agonists vs placebo

Multiple pregnancy rate · women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes

The review found no eligible studies for this question.

1 finding from 1 review

Endometrial preparation for women undergoing embryo transfer with frozen embryos or embryos derived from donor oocytes 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Gonadotropins with GnRH agonists vs gonadotropins alone

Multiple pregnancy rate · intrauterine insemination (IUI) in women with infertility

It is very uncertain whether gonadotropins with GnRH agonists changes multiple pregnancy rate per couple compared with gonadotropins alone (very low certainty).

1 finding from 1 review

Agents for ovarian stimulation for intrauterine insemination (IUI) in ovulatory women with infertility 2021 · Cochrane Headline outcomes only
OR 2.53 [0.82, 7.86]
2 studies · 264 participants
Very low