Findings

What do systematic reviews say?

5 questions · 5 findings · 2 reviews · Anaesthesia

Sort:Best matchNewest Highest certainty Download CSV

No studies found 0 · 0%GRADE not reported 1 · 20%Very low 0 · 0%Low 0 · 0%Moderate 2 · 40%High 2 · 40%

rHuEPO with iron vs control treatment with or without iron

Mortality (within 30 days after surgery) · adult participants, irrespective of gender and type of non‐cardiac surgery, with mild or severe preoperative anaemia

rHuEPO with iron showed no clear difference in mortality (within 30 days after surgery) compared with control treatment with or without iron (moderate certainty).

1 finding from 1 review

Erythropoietin plus iron versus control treatment including placebo or iron for preoperative anaemic adults undergoing… 2020 · Cochrane Headline outcomes only
RR 1.18 [0.39, 3.63]
2 studies · 230 participants
Moderate

Alpha2‐adrenergic agonist vs control

All‐cause mortality (within 30‐days after surgery: any reported death) · adults undergoing non‐cardiac surgery

1 finding from 1 review

Alpha‐2 adrenergic agonists for the prevention of cardiac complications among adults undergoing surgery 2018 · Cochrane Headline outcomes only
no estimate extracted
16 studies · 14081 participants
High

Alpha2‐adrenergic agonist vs control

All‐cause mortality (within 30‐days after surgery: any reported death) · adults undergoing cardiac surgery

Alpha‐2 adrenergic agonists showed no clear difference in all‐cause mortality (within 30‐days after surgery: any reported death) compared with control (moderate certainty).

1 finding from 1 review

Alpha‐2 adrenergic agonists for the prevention of cardiac complications among adults undergoing surgery 2018 · Cochrane Headline outcomes only
RR 0.52 [0.26, 1.04]
16 studies · 1947 participants
Moderate

Alpha2‐adrenergic agonist vs control

Cardiac mortality · adults undergoing cardiac surgery

1 finding from 1 review

Alpha‐2 adrenergic agonists for the prevention of cardiac complications among adults undergoing surgery 2018 · Cochrane Headline outcomes only
no estimate extracted
1 study · 22 participants
GRADE not reported

Alpha2‐adrenergic agonist vs control

Cardiac mortality · adults undergoing non‐cardiac surgery

1 finding from 1 review

Alpha‐2 adrenergic agonists for the prevention of cardiac complications among adults undergoing surgery 2018 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 12525 participants
High