Findings

What do systematic reviews say?

8 questions · 9 findings · 4 reviews · Vascular

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No studies found 2 · 22.2%GRADE not reported 1 · 11.1%Very low 1 · 11.1%Low 4 · 44.4%Moderate 1 · 11.1%High 0 · 0%

Duplex ultrasound plus pulse palpation and arterial pressure index (ABI or TBI) vs pulse palpation plus arterial pressure index (ABI or TBI) (long term)

All‐cause mortality · people who underwent a lower limb revascularisation

The review found no eligible studies for this question.

1 finding from 1 review

Duplex ultrasound for surveillance of lower limb revascularisation 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Duplex ultrasound plus pulse palpation and arterial pressure index (ABI or TBI) vs pulse palpation plus arterial pressure index (ABI or TBI) (short term)

All‐cause mortality · people who underwent a lower limb revascularisation

Duplex ultrasound plus pulse palpation and arterial pressure index… showed no clear difference in all‐cause mortality compared with pulse palpation plus arterial pressure index (ABI or TBI) (short term) (low certainty).

1 finding from 1 review

Duplex ultrasound for surveillance of lower limb revascularisation 2023 · Cochrane Headline outcomes only
RR 1.11 [0.7, 1.74]
1 study · 594 participants
Low

Oral factor Xa inhibitors vs conventional anticoagulation

All‐cause mortality · patients with a pulmonary embolism, confirmed by standard imaging techniques

Oral factor Xa inhibitors showed no clear difference in all‐cause mortality compared with conventional anticoagulation (moderate certainty).

1 finding from 1 review

Oral direct thrombin inhibitors or oral factor Xa inhibitors versus conventional anticoagulants for the treatment of… 2023 · Cochrane Headline outcomes only
OR 1.16 [0.79, 1.7]
1 study · 4817 participants
Moderate

Oral direct thrombin inhibitors (DTIs) vs conventional anticoagulation

All‐cause mortality · patients with a pulmonary embolism, confirmed by standard imaging techniques

The review found no eligible studies for this question.

1 finding from 1 review

Oral direct thrombin inhibitors or oral factor Xa inhibitors versus conventional anticoagulants for the treatment of… 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Outpatient vs inpatient treatment

Long‐term all‐cause mortality · people with low‐risk acute pulmonary embolism

Outpatient showed no clear difference in long‐term all‐cause mortality compared with inpatient treatment (low certainty).

1 finding from 1 review

Outpatient versus inpatient treatment for acute pulmonary embolism 2022 · Cochrane Headline outcomes only
RR 0.98 [0.06, 15.58]
2 studies · 451 participants
Low

Outpatient vs inpatient treatment

Short‐term all‐cause mortality · people with low‐risk acute pulmonary embolism

2 findings from 1 review

Outpatient versus inpatient treatment for acute pulmonary embolism 2022 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 453 participants
Low
Outpatient versus inpatient treatment for acute pulmonary embolism 2022 · Cochrane Headline outcomes only
RR 0.33 [0.01, 7.98]
2 studies · 453 participants
Low

Ultrasound‐assisted catheter‐directed thrombolysis plus standard intravenous heparinisation vs standard intravenous heparinisation

All‐cause mortality(7‐day) · people with intermediate‐risk (submassive) APE

1 finding from 1 review

Catheter‐directed therapies for the treatment of high risk (massive) and intermediate risk (submassive) acute… 2022 · Cochrane Headline outcomes only
no estimate extracted
1 study · 59 participants
GRADE not reported

Ultrasound‐assisted catheter‐directed thrombolysis plus standard intravenous heparinisation vs standard intravenous heparinisation

All‐cause mortality (90‐day) · people with intermediate‐risk (submassive) APE

It is very uncertain whether ultrasound‐assisted catheter‐directed thrombolysis plus standard… changes all‐cause mortality (90‐day) compared with standard intravenous heparinisation (very low certainty).

1 finding from 1 review

Catheter‐directed therapies for the treatment of high risk (massive) and intermediate risk (submassive) acute… 2022 · Cochrane Headline outcomes only
OR 0.31 [0.01, 7.96]
1 study · 59 participants
Very low