Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3 questions · 3 findings · 3 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 33.3%Low 1 · 33.3%Moderate 1 · 33.3%High 0 · 0%

Once‐daily ICS/LABA combined inhalers vs once‐daily LAMA

Mortality (all‐cause) · patients with chronic obstructive pulmonary disease

It is very uncertain whether once‐daily ICS/LABA combined inhalers changes mortality (all‐cause) compared with once‐daily LAMA (very low certainty).

1 finding from 1 review

Tiotropium + LABA/ICS combination vs tiotropium

Mortality (all‐cause) · patients with chronic obstructive pulmonary disease

Tiotropium + LABA/ICS combination showed no clear difference in mortality (all‐cause) compared with tiotropium (moderate certainty).

1 finding from 1 review