Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

12 questions · 14 findings · 6 reviews · Acute Respiratory Infections

No studies found 4 · 28.6%GRADE not reported 5 · 35.7%Very low 1 · 7.1%Low 2 · 14.3%Moderate 2 · 14.3%High 0 · 0%

Xylitol vs control

Mortality ‐ not reported · preventing acute otitis media in children up to 12 years of age
3 findings from 1 review

Intervention not reported

Mortality in children with HIV infection ‐ isoniazid prophylaxis only · children with HIV infection aged 12 years and under

The intervention showed no clear difference in mortality in children with HIV infection ‐ isoniazid prophylaxis only (low certainty).

1 finding from 1 review

Intervention not reported

Mortality in children with HIV infection ‐ co‐trimoxazole prophylaxis only · children with HIV infection aged 12 years and under

The intervention probably leads to lower mortality in children with HIV infection ‐ co‐trimoxazole… (moderate certainty).

1 finding from 1 review

Intervention not reported

Mortality (deaths during trial period) · adults (> 18 years of age) with either COPD or recurrent acute exacerbations of chronic bronchitis

It is very uncertain whether the intervention changes mortality (deaths during trial period) (very low certainty).

1 finding from 1 review