All‐cause mortality · Critically ill patients receiving mechanical ventilation in ICU
1 finding from 1 review
Potassium permanganate versus placebo (Meidani 2018, 100 participants): no evidence of a difference in mortality; single study.
1 study · 100 participants
GRADE not reported
All‐cause mortality · Critically ill adults receiving mechanical ventilation in ICU
Toothbrushing (with or without antiseptics), as part of oral hygiene… showed no clear difference in mortality compared with no toothbrushing (with or without antiseptics) (low certainty).
1 finding from 1 review
All‐cause mortality · Critically ill patients receiving mechanical ventilation in ICU
Povidone iodine rinse showed no clear difference in mortality compared with saline rinse or placebo; GRADE not reported.
1 finding from 1 review
All‐cause mortality · Critically ill patients (adults and children) receiving mechanical ventilation in ICU
Chlorhexidine (mouthrinse or gel), as part of oral hygiene care showed no clear difference in mortality compared with placebo or usual care (moderate certainty).
1 finding from 1 review
All‐cause mortality · Critically ill patients receiving mechanical ventilation in ICU
Chlorhexidine showed no clear difference in mortality compared with potassium permanganate; GRADE not reported.
1 finding from 1 review
RR 1.11 [0.89, 1.38]
2 studies
GRADE not reported
All‐cause mortality · Critically ill patients receiving mechanical ventilation in ICU
Saline rinse led to lower mortality compared with saline-soaked swab; GRADE not reported.
1 finding from 1 review
All‐cause mortality · Critically ill patients receiving mechanical ventilation in ICU
1 finding from 1 review
All‐cause mortality · Critically ill patients receiving mechanical ventilation in ICU
Powered toothbrushing (as part of comprehensive oral care) showed no clear difference in mortality compared with manual toothbrushing (standard oral care); GRADE not reported.
1 finding from 1 review
All‐cause mortality · Critically ill patients receiving mechanical ventilation in ICU
1 finding from 1 review
Povidone iodine versus usual care: single study (67 participants), no evidence of a difference in mortality.
1 study · 67 participants
GRADE not reported
All‐cause mortality · Critically ill patients receiving mechanical ventilation in ICU
Saline rinse showed no clear difference in mortality compared with usual care (no rinse); GRADE not reported.
1 finding from 1 review
All‐cause mortality · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials…
It is very uncertain whether altered fractionation radiotherapy (hyperfractionated and/or… changes mortality compared with conventional (standard) fractionation radiotherapy (very low certainty).
2 findings from 1 review
Total mortality · Adults with oral cavity or oropharyngeal cancer
It is very uncertain whether surgery plus radiotherapy changes total mortality compared with radiotherapy alone (very low certainty).
1 finding from 1 review
Total mortality · Adults with oral cavity cancer
1 finding from 1 review
Total mortality: 2 trials reported HR but could not be pooled (different surgical procedures); neither indicated a difference (BHNCSG 1998 HR 1.14, 0.70 to 1.86; Bier 1994 HR 0.87, 0.41 to 1.83); 252 participants (2…
2 studies · 252 participants
Very low
Total mortality · Adults with oropharyngeal cancer
Surgery showed no clear difference in total mortality compared with radiotherapy alone (low certainty).
1 finding from 1 review
Total mortality · Adults with oral cavity or oropharyngeal cancer
1 finding from 1 review
Total mortality: study reported survival significantly better with surgery and RT vs chemoradiotherapy, but no useable data; 32 participants (1 RCT, Iyer 2015 oral cavity subgroup).
1 study · 32 participants
Very low
Total mortality · Adults with oral cavity or oropharyngeal cancer with nodal disease (stage N2 or N3)
PET-CT following chemoradiotherapy (neck dissection only if… showed no clear difference in total mortality compared with planned neck dissection before or after chemoradiotherapy (moderate certainty).
1 finding from 1 review
Total mortality · Adults with oral cavity cancer (tongue or floor of mouth) and clinically negative neck nodes
The review found no eligible studies for this question.
1 finding from 1 review
Total mortality · Adults with oral cavity or oropharyngeal cancer
Sentinel node biopsy (neck dissection only if biopsy positive) showed no clear difference in total mortality compared with elective neck dissection (low certainty).
1 finding from 1 review
Total mortality · Adults with oral cavity or oropharyngeal cancer
1 finding from 1 review
Total mortality · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials…
1 finding from 1 review
Hyperfractionated/accelerated split course vs accelerated boost (Fu 1995, feasibility study, 75 participants): authors report no significant difference in total mortality; data not presented in a way that allows…
1 study · 75 participants
GRADE not reported