Findings

What do systematic reviews say?

5 questions · 5 findings · 2 reviews · All outcomes

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No studies found 0 · 0%GRADE not reported 2 · 40%Very low 1 · 20%Low 1 · 20%Moderate 1 · 20%High 0 · 0%

Professional oral care vs Usual oral care

Mortality (all‐cause) · Residents of nursing homes and other long-term care facilities

1 finding from 1 review

Oral care measures for preventing nursing home‐acquired pneumonia 2022 · Cochrane All outcomes
12-30 months
All-cause mortality, follow-up 12-30 months, 3764 (3 studies), Very low. Not pooled. Adachi RR 0.80 (0.40 to 1.58; 88); Juthani-Mehta HR 1.16 (0.88 to 1.53; 834); Zimmerman adjusted IRR 0.83 (0.61 to 1.12; 1606).…
3 studies · 3764 participants
Very low

Professional oral care vs Usual oral care

Mortality (pneumonia-associated) · Residents of nursing homes and other long-term care facilities

Professional oral care may leads to lower mortality (pneumonia-associated) compared with usual oral care (low certainty).

1 finding from 1 review

Oral care measures for preventing nursing home‐acquired pneumonia 2022 · Cochrane All outcomes
24 months
RR 0.43 [0.25, 0.76]
2 studies · 454 participants
Low

Chlorhexidine (mouthrinse or gel), as part of oral hygiene care vs placebo or usual care

All‐cause mortality · Critically ill patients (adults and children) receiving mechanical ventilation in ICU

Chlorhexidine (mouthrinse or gel), as part of oral hygiene care showed no clear difference in mortality compared with placebo or usual care (moderate certainty).

1 finding from 1 review

Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia 2020 · Cochrane All outcomes
Follow-up: mean 1 month
RR 1.03 [0.80, 1.33]
9 studies · 944 participants
Moderate

Povidone iodine rinse vs usual or supportive care

All‐cause mortality · Critically ill patients receiving mechanical ventilation in ICU

1 finding from 1 review

Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia 2020 · Cochrane All outcomes
Povidone iodine versus usual care: single study (67 participants), no evidence of a difference in mortality.
1 study · 67 participants
GRADE not reported

Saline rinse vs usual or supportive care

All‐cause mortality · Critically ill patients receiving mechanical ventilation in ICU

Saline rinse showed no clear difference in mortality compared with usual care (no rinse); GRADE not reported.

1 finding from 1 review

Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia 2020 · Cochrane All outcomes
RR 1.10 [0.87, 1.39]
2 studies · 324 participants
GRADE not reported