Findings

What do systematic reviews say?

8 questions · 8 findings · 3 reviews · Infectious Diseases

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 25%Low 6 · 75%Moderate 0 · 0%High 0 · 0%

Rapid susceptibility methods vs standard methods versus placebo

All‐cause mortality · people with bloodstream infections

Rapid susceptibility methods showed no clear difference in mortality compared with standard methods versus placebo (low certainty).

1 finding from 1 review

Rapid versus standard antimicrobial susceptibility testing to guide treatment of bloodstream infection 2021 · Cochrane Headline outcomes only
RR 1.1 [0.82, 1.46]
6 studies · 1638 participants
Low

Malaria rapid diagnostic test (mRDT) vs clinical diagnosis

All‐cause mortality · people with suspected malaria

1 finding from 1 review

Adding rapid diagnostic tests to community‐based programmes for treating malaria 2022 · Cochrane Headline outcomes only
no estimate extracted
7678 participants
Very low

Rapid antiretroviral therapy (ART) vs usual care

Mortality at 12 months · people living with HIV

It is very uncertain whether rapid antiretroviral therapy (ART) changes mortality at 12 months compared with standard care (very low certainty).

1 finding from 1 review

Rapid initiation of antiretroviral therapy for people living with HIV 2019 · Cochrane Headline outcomes only
RR 0.72 [0.51, 1.01]
7 studies · 5451 participants
Very low

Rapid susceptibility methods vs standard methods versus placebo

Mortality (with stewardship) · people with bloodstream infections

Rapid susceptibility methods showed no clear difference in mortality (with stewardship) compared with standard methods versus placebo (low certainty).

1 finding from 1 review

Rapid versus standard antimicrobial susceptibility testing to guide treatment of bloodstream infection 2021 · Cochrane Headline outcomes only
RR 1.17 [0.81, 1.7]
4 studies · 1404 participants
Low

Rapid susceptibility methods vs standard methods versus placebo

Mortality (subgroup genotypic) · people with bloodstream infections

Rapid susceptibility methods showed no clear difference in mortality (subgroup genotypic) compared with standard methods versus placebo (low certainty).

1 finding from 1 review

Rapid versus standard antimicrobial susceptibility testing to guide treatment of bloodstream infection 2021 · Cochrane Headline outcomes only
RR 1.02 [0.69, 1.49]
4 studies · 1074 participants
Low

Rapid susceptibility methods vs standard methods versus placebo

Mortality (subgroup phenotypic) · people with bloodstream infections

Rapid susceptibility methods showed no clear difference in mortality (subgroup phenotypic) compared with standard methods versus placebo (low certainty).

1 finding from 1 review

Rapid versus standard antimicrobial susceptibility testing to guide treatment of bloodstream infection 2021 · Cochrane Headline outcomes only
RR 1.37 [0.8, 2.35]
2 studies · 564 participants
Low

Rapid susceptibility methods vs standard methods versus placebo

Mortality (without stewardship) · people with bloodstream infections

Rapid susceptibility methods showed no clear difference in mortality (without stewardship) compared with standard methods versus placebo (low certainty).

1 finding from 1 review

Rapid versus standard antimicrobial susceptibility testing to guide treatment of bloodstream infection 2021 · Cochrane Headline outcomes only
RR 0.89 [0.35, 2.27]
2 studies · 234 participants
Low

Malaria rapid diagnostic test (mRDT) in community‐based care vs health facility care

All‐cause mortality and malaria mortality · people with suspected malaria

1 finding from 1 review

Adding rapid diagnostic tests to community‐based programmes for treating malaria 2022 · Cochrane Headline outcomes only
no estimate extracted
9428 participants
Low