All‐cause mortality · Critically ill patients receiving mechanical ventilation in ICU
Powered toothbrushing (as part of comprehensive oral care) showed no clear difference in mortality compared with manual toothbrushing (standard oral care); GRADE not reported.
1 finding from 1 review
Total mortality · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials…
Pre-operative radiotherapy (plus surgery) showed no clear difference in total mortality compared with surgery alone; GRADE not reported.
1 finding from 1 review
HR 0.83 [0.64, 1.07]
1 study
GRADE not reported
Total mortality · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials…
Pre-operative and post-operative radiotherapy showed no clear difference in total mortality compared with post-operative radiotherapy alone; GRADE not reported.
1 finding from 1 review
HR 0.67 [0.35, 1.28]
1 study
GRADE not reported
Total mortality · Adults with oral cavity cancer
1 finding from 1 review
Total mortality: 2 trials reported HR but could not be pooled (different surgical procedures); neither indicated a difference (BHNCSG 1998 HR 1.14, 0.70 to 1.86; Bier 1994 HR 0.87, 0.41 to 1.83); 252 participants (2…
2 studies · 252 participants
Very low
Disease-free survival · Adults with oral cavity cancer
It is very uncertain whether elective radical (comprehensive) neck dissection changes disease-free survival (new disease, progression, and mortality) compared with elective selective neck dissection (very low certainty).
1 finding from 1 review
Maternal death · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination
The review found no eligible studies for this question.
1 finding from 1 review
Maternal death · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination
1 finding from 1 review
All‐cause mortality · Critically ill patients receiving mechanical ventilation in ICU
1 finding from 1 review
Potassium permanganate versus placebo (Meidani 2018, 100 participants): no evidence of a difference in mortality; single study.
1 study · 100 participants
GRADE not reported
All‐cause mortality · Critically ill adults receiving mechanical ventilation in ICU
Toothbrushing (with or without antiseptics), as part of oral hygiene… showed no clear difference in mortality compared with no toothbrushing (with or without antiseptics) (low certainty).
1 finding from 1 review
All‐cause mortality · Critically ill patients receiving mechanical ventilation in ICU
Povidone iodine rinse showed no clear difference in mortality compared with saline rinse or placebo; GRADE not reported.
1 finding from 1 review
All‐cause mortality · Critically ill patients (adults and children) receiving mechanical ventilation in ICU
Chlorhexidine (mouthrinse or gel), as part of oral hygiene care showed no clear difference in mortality compared with placebo or usual care (moderate certainty).
1 finding from 1 review
All‐cause mortality · Critically ill patients receiving mechanical ventilation in ICU
Chlorhexidine showed no clear difference in mortality compared with potassium permanganate; GRADE not reported.
1 finding from 1 review
RR 1.11 [0.89, 1.38]
2 studies
GRADE not reported
All‐cause mortality · Critically ill patients receiving mechanical ventilation in ICU
Saline rinse led to lower mortality compared with saline-soaked swab; GRADE not reported.
1 finding from 1 review
All‐cause mortality · Critically ill patients receiving mechanical ventilation in ICU
1 finding from 1 review
All‐cause mortality · Critically ill patients receiving mechanical ventilation in ICU
1 finding from 1 review
Povidone iodine versus usual care: single study (67 participants), no evidence of a difference in mortality.
1 study · 67 participants
GRADE not reported
All‐cause mortality · Critically ill patients receiving mechanical ventilation in ICU
Saline rinse showed no clear difference in mortality compared with usual care (no rinse); GRADE not reported.
1 finding from 1 review
Mortality or serious adverse events requiring hospital admission · Adults or children at increased risk of bacterial endocarditis (pre-existing cardiac condition) undergoing an invasive dental procedure
The review found no eligible studies for this question.
1 finding from 1 review
Perinatal mortality · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination
It is very uncertain whether periodontal treatment (scaling and root planing, alone or with… changes perinatal mortality (including fetal and neonatal deaths up to the… compared with alternative (less intensive) periodontal treatment, alone or with… (very low certainty).
1 finding from 1 review
Perinatal mortality · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination
It is very uncertain whether periodontal treatment (scaling and root planing, polishing, or… changes perinatal mortality (including fetal and neonatal deaths up to the… compared with no treatment (very low certainty).
1 finding from 1 review
Mortality (all‐cause) · Residents of nursing homes and other long-term care facilities
1 finding from 1 review
All-cause mortality, follow-up 12-30 months, 3764 (3 studies), Very low. Not pooled. Adachi RR 0.80 (0.40 to 1.58; 88); Juthani-Mehta HR 1.16 (0.88 to 1.53; 834); Zimmerman adjusted IRR 0.83 (0.61 to 1.12; 1606).…
3 studies · 3764 participants
Very low