Findings

What do systematic reviews say?

6 questions · 6 findings · 3 reviews

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No studies found 1 · 16.7%GRADE not reported 2 · 33.3%Very low 1 · 16.7%Low 2 · 33.3%Moderate 0 · 0%High 0 · 0%

Povidone iodine rinse vs Saline rinse or placebo

All‐cause mortality · Critically ill patients receiving mechanical ventilation in ICU

Povidone iodine rinse showed no clear difference in mortality compared with saline rinse or placebo; GRADE not reported.

1 finding from 1 review

Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia 2020 · Cochrane All outcomes
RR 1.00 [0.66, 1.50]
2 studies · 217 participants
GRADE not reported

Povidone iodine rinse vs usual or supportive care

All‐cause mortality · Critically ill patients receiving mechanical ventilation in ICU

1 finding from 1 review

Oral hygiene care for critically ill patients to prevent ventilator‐associated pneumonia 2020 · Cochrane All outcomes
Povidone iodine versus usual care: single study (67 participants), no evidence of a difference in mortality.
1 study · 67 participants
GRADE not reported

Chlorhexidine vs povidone‐iodine

All‐cause mortality ‐ Chlorhexidine in alcohol versus povidone‐iodine in aqueous solution Clinical assessment · patients with a central venous catheter

Chlorhexidine showed no clear difference in all‐cause mortality ‐ Chlorhexidine in alcohol versus… compared with povidone‐iodine (low certainty).

1 finding from 1 review

Skin antisepsis for reducing central venous catheter‐related infections 2016 · Cochrane Headline outcomes only
RR 0.8 [0.48, 1.34]
1 study · 222 participants
Low

Chlorhexidine vs povidone‐iodine

All‐cause mortality ‐ Chlorhexidine in aqueous solution versus povidone‐iodine in aqueous solution Clinical assessment · patients with a central venous catheter

Chlorhexidine showed no clear difference in all‐cause mortality ‐ Chlorhexidine in aqueous solution versus… compared with povidone‐iodine (low certainty).

1 finding from 1 review

Skin antisepsis for reducing central venous catheter‐related infections 2016 · Cochrane Headline outcomes only
RR 1.15 [0.72, 1.83]
1 study · 213 participants
Low

Intervention vs any comparison

Mortality ‐ Topical povidone iodine gel versus no topical povidone iodine gel · patients undergoing liver resections

It is very uncertain whether intervention changes mortality ‐ Topical povidone iodine gel versus no topical povidone… compared with comparison (very low certainty).

1 finding from 1 review

Methods of decreasing infection to improve outcomes after liver resections 2011 · Cochrane Headline outcomes only
RR 1.35 [0.24, 7.53]
1 study · 59 participants
Very low

Chlorhexidine vs povidone‐iodine

Mortality attributable the CVC‐related infections. · patients with a central venous catheter

The review found no eligible studies for this question.

1 finding from 1 review

Skin antisepsis for reducing central venous catheter‐related infections 2016 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found