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Evidence found and GRADE certainty

3 questions · 3 findings · 2 reviews · Injuries

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 33.3%Low 2 · 66.7%Moderate 0 · 0%High 0 · 0%

SDAC + hospital intervention vs hospital intervention

Incidence of mortality · first aid in patients with acute oral poisoning (not specified, tricyclic antidepressants, combinations of different drugs or yellow…

SDAC + hospital intervention showed no clear difference in incidence of mortality compared with hospital intervention alone (low certainty).

1 finding from 1 review

Intravenous tranexamic acid vs placebo

All‐cause mortality (30 days post‐surgery) · people undergoing definitive fixation of hip, pelvic and long bone fractures

Intravenous tranexamic acid showed no clear difference in all‐cause mortality (30 days post‐surgery) compared with placebo (low certainty).

1 finding from 1 review

Antifibrinolytic therapy - locally-applied tranexamic acid (TXA) mouthwash/solution (SoF eligibility: TXA or EACA; all included trials used topical TXA) vs placebo

All‐cause mortality (30 days post‐surgery) · people undergoing definitive fixation of hip, pelvic and long bone fractures

It is very uncertain whether topical tranexamic acid changes all‐cause mortality (30 days post‐surgery) compared with placebo (very low certainty).

1 finding from 1 review