Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

16 questions · 16 findings · 6 reviews · Headline outcomes only

No studies found 1 · 6.3%GRADE not reported 0 · 0%Very low 0 · 0%Low 7 · 43.8%Moderate 8 · 50%High 0 · 0%

Dinutuximab‐containing immunotherapy vs usual care

Overall survival (reported as mortality) · People with high‐risk neuroblastoma pre‐treated with autologous haematopoietic stem cell transplantation

Dinutuximab‐containing immunotherapy probably leads to lower overall survival (reported as mortality) compared with standard therapy (moderate certainty).

1 finding from 1 review

Dinutuximab‐containing immunotherapy vs usual care

Treatment‐related mortality ‐ not reported · People with high‐risk neuroblastoma pre‐treated with autologous haematopoietic stem cell transplantation

The review found no eligible studies for this question.

1 finding from 1 review

Dinutuximab‐containing immunotherapy vs usual care

Event‐free survival · People with high‐risk neuroblastoma pre‐treated with autologous haematopoietic stem cell transplantation

Dinutuximab‐containing immunotherapy probably leads to lower event‐free survival (reported as relapse, progressive disease,… compared with standard therapy (moderate certainty).

1 finding from 1 review