Findings

What do systematic reviews say?

3 questions · 4 findings · 1 reviews · Heart

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 1 · 25%High 3 · 75%

All‐cause mortality maximum · patients with coronary heart disease

Antibiotics showed no clear difference in all‐cause mortality at maximum compared with placebo or no intervention (high certainty).

1 finding from 1 review

Antibiotics for secondary prevention of coronary heart disease 2021 · Cochrane Headline outcomes only
RR 1.06 [0.99, 1.13]
20 studies · 25774 participants
High

All‐cause mortality at 24±6 months · patients with coronary heart disease

Antibiotics leads to higher all‐cause mortality at 24±6 months compared with placebo or no intervention (high certainty).

1 finding from 1 review

Antibiotics for secondary prevention of coronary heart disease 2021 · Cochrane Headline outcomes only
RR 1.25 [1.06, 1.48]
6 studies · 9517 participants
High

Cardiovascular mortality · patients with coronary heart disease

Antibiotics leads to higher cardiovascular mortality at 24±6 months compared with placebo or no intervention (high certainty).

2 findings from 1 review

Antibiotics for secondary prevention of coronary heart disease 2021 · Cochrane Headline outcomes only
RR 1.5 [1.17, 1.91]
5 studies · 9044 participants
High
Antibiotics for secondary prevention of coronary heart disease 2021 · Cochrane Headline outcomes only
RR 1.11 [0.98, 1.25]
2 studies · 4674 participants
Moderate