Findings

What do systematic reviews say?

22 questions · 22 findings · 14 reviews

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No studies found 2 · 9.1%GRADE not reported 3 · 13.6%Very low 2 · 9.1%Low 9 · 40.9%Moderate 6 · 27.3%High 0 · 0%

Pre-operative and post-operative radiotherapy vs Post-operative radiotherapy alone

Total mortality · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials…

Pre-operative and post-operative radiotherapy showed no clear difference in total mortality compared with post-operative radiotherapy alone; GRADE not reported.

1 finding from 1 review

Interventions for the treatment of oral cavity and oropharyngeal cancer: radiotherapy 2010 · Cochrane All outcomes
HR 0.67 [0.35, 1.28]
1 study
GRADE not reported

TACE followed by 3‐DCRT vs chemoembolisation

All‐cause mortality: at 3 years · primary hepatocellular carcinoma

TACE followed by 3‐DCRT may leads to lower all‐cause mortality: at 3 years compared with TACE (low certainty).

1 finding from 1 review

Transcatheter arterial chemoembolisation followed by three‐dimensional conformal radiotherapy versus transcatheter… 2019 · Cochrane Headline outcomes only
RR 0.8 [0.73, 0.88]
7 studies · 552 participants
Low