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Evidence found and GRADE certainty

6 questions · 6 findings · 1 reviews · Skin

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No studies found 1 · 16.7%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 33.3%Moderate 3 · 50%High 0 · 0%

Acyclovir vs placebo, vitamins, or no treatment

Minor adverse events not leading to withdrawal of treatment · pityriasis rosea

Acyclovir showed no clear difference in minor participant‐reported adverse events not requiring withdrawal… compared with placebo, vitamins, or no treatment (moderate certainty).

1 finding from 1 review

Clarithromycin vs placebo

Minor adverse events not leading to withdrawal of treatment · pityriasis rosea

The review found no eligible studies for this question.

1 finding from 1 review

Acyclovir + calamine + cetirizine vs calamine + cetirizine

Minor participant‐reported adverse events not requiring withdrawal of the treatment: Headache. · pityriasis rosea

Acyclovir + calamine + cetirizine showed no clear difference in minor participant‐reported adverse events not requiring withdrawal… compared with calamine + cetirizine (low certainty).

1 finding from 1 review

Azithromycin vs placebo or vitamins

Minor participant‐reported adverse events not requiring withdrawal of the treatment: Mild abdominal pain. · pityriasis rosea

Azithromycin showed no clear difference in minor participant‐reported adverse events not requiring withdrawal… compared with placebo or vitamins (moderate certainty).

1 finding from 1 review

Erythromycin vs placebo

Adverse events: minor gastrointestinal symptoms · pityriasis rosea

Erythromycin showed no clear difference in minor participant‐reported adverse events not requiring withdrawal… compared with placebo (moderate certainty).

1 finding from 1 review