Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

3 questions · 3 findings · 1 reviews · Skin

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 66.7%Moderate 1 · 33.3%High 0 · 0%

Acyclovir vs placebo, vitamins, or no treatment

Minor adverse events not leading to withdrawal of treatment · pityriasis rosea

Acyclovir showed no clear difference in minor participant‐reported adverse events not requiring withdrawal… compared with placebo, vitamins, or no treatment (moderate certainty).

1 finding from 1 review

Acyclovir + calamine + cetirizine vs calamine + cetirizine

Minor participant‐reported adverse events not requiring withdrawal of the treatment: Headache. · pityriasis rosea

Acyclovir + calamine + cetirizine showed no clear difference in minor participant‐reported adverse events not requiring withdrawal… compared with calamine + cetirizine (low certainty).

1 finding from 1 review