What do systematic reviews say?

DOAC vs variable dose warfarin

Direct oral anticoagulants (DOAC) showed no clear difference in minor bleeding compared with warfarin (low certainty).

• Direct oral anticoagulants versus warfarin for preventing stroke and systemic embolic events among atrial fibrillation… 2017 · Cochrane Headline outcomes only
  RR 0.97 [0.58, 1.61]
  2 studies · 3012 participants
  Low