Findings

What do systematic reviews say?

1 questions · 2 findings · 1 reviews · Gut

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 50%Moderate 1 · 50%High 0 · 0%

Maintenance of clinical remission · Participants with Crohn's disease in remission

Methotrexate probably leads to higher proportion of patients maintaining clinical remission (high dose… compared with placebo (moderate certainty).

2 findings from 1 review

Methotrexate for maintenance of remission in Crohn's disease 2014 · Cochrane Headline outcomes only
RR 1.67 [1.05, 2.67]
1 study · 76 participants
Moderate
Methotrexate for maintenance of remission in Crohn's disease 2014 · Cochrane Headline outcomes only
RR 1.35 [0.86, 2.12]
1 study · 22 participants
Low