Findings

What do systematic reviews say?

5 questions · 5 findings · 2 reviews · Haematology

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 40%Moderate 3 · 60%High 0 · 0%

Anti‐leukaemic therapy plus alemtuzumab vs anti‐leukaemic therapy alone (anti‐leukaemic therapy identical

Overall survival: Median length of · people with chronic lymphocytic leukaemia

Anti‐leukaemic therapy plus alemtuzumab probably leads to lower overall survival (median 2 years) compared with anti‐leukaemic therapy alone (anti‐leukaemic therapy identical (moderate certainty).

1 finding from 1 review

Alemtuzumab for patients with chronic lymphocytic leukaemia 2012 · Cochrane Headline outcomes only
HR 0.65 [0.45, 0.94]
1 study · 335 participants
Moderate

Intervention not reported

Overall survival [range of median · patients with APL in first complete remission

The intervention may leads to lower overall survival [range of median (low certainty).

1 finding from 1 review

The role of maintenance therapy in acute promyelocytic leukemia in the first complete remission 2013 · Cochrane Headline outcomes only
no estimate extracted
892 participants
Low

Intervention not reported

Overall survival [range of median · patients with APL in first complete remission

The intervention probably leads to lower overall survival [range of median (moderate certainty).

1 finding from 1 review

The role of maintenance therapy in acute promyelocytic leukemia in the first complete remission 2013 · Cochrane Headline outcomes only
no estimate extracted
632 participants
Moderate

Intervention not reported

Overall survival [range of median · patients with APL in first complete remission

The intervention probably leads to lower overall survival [range of median (moderate certainty).

1 finding from 1 review

The role of maintenance therapy in acute promyelocytic leukemia in the first complete remission 2013 · Cochrane Headline outcomes only
no estimate extracted
1033 participants
Moderate

Intervention not reported

Subgroup analysis in pediatric patients: Overall survival [range of median · patients with APL in first complete remission

The intervention may leads to lower subgroup analysis in pediatric patients: Overall survival [range of… (low certainty).

1 finding from 1 review

The role of maintenance therapy in acute promyelocytic leukemia in the first complete remission 2013 · Cochrane Headline outcomes only
no estimate extracted
133 participants
Low