Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Neonatal

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Barbiturate treatment vs placebo or no treatment

Major neurodevelopmental disability at childhood · infants with perinatal asphyxia

It is very uncertain whether barbiturate treatment changes major neurodevelopmental disability compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Prophylactic barbiturate use for the prevention of morbidity and mortality following perinatal asphyxia 2016 · Cochrane Headline outcomes only
RR 0.24 [0.06, 0.92]
1 study · 31 participants
Very low

Barbiturate treatment vs placebo or no treatment

Death or major neurodevelopmental disability · infants with perinatal asphyxia

It is very uncertain whether barbiturate treatment changes death or major neurodevelopmental disability compared with placebo or no treatment (very low certainty).

1 finding from 1 review

Prophylactic barbiturate use for the prevention of morbidity and mortality following perinatal asphyxia 2016 · Cochrane Headline outcomes only
RR 0.33 [0.14, 0.78]
1 study · 31 participants
Very low