Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews · Oral Health

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No studies found 0 · 0%GRADE not reported 3 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Genetically predicted DMFS (dental caries) vs Lower genetically predicted DMFS

Lumbar spine bone mineral density (BMD) · European GWAS participants

The SVMR IVW interval excluded zero.

1 finding from 1 review

From teeth to bone: dental caries has causal effects on osteoporosis and osteoporotic fracture. 2025 All outcomes
Summary-level GWAS · SVMR IVW
BETA 0.105 [0.006, 0.205]
28498 participants
GRADE not reported

Genetically predicted DMFS (dental caries) vs Lower genetically predicted DMFS, adjusted for periodontitis

Lumbar spine bone mineral density (BMD) · European GWAS participants

The MVMR IVW interval excluded zero.

1 finding from 1 review

From teeth to bone: dental caries has causal effects on osteoporosis and osteoporotic fracture. 2025 All outcomes
Summary-level GWAS · MVMR IVW
BETA 0.105 [0.011, 0.199]
28498 participants
GRADE not reported

Genetically predicted periodontitis vs Lower genetically predicted periodontitis liability, adjusted for DMFS

Lumbar spine bone mineral density (BMD) · European GWAS participants

The MVMR IVW interval included zero.

1 finding from 1 review

From teeth to bone: dental caries has causal effects on osteoporosis and osteoporotic fracture. 2025 All outcomes
Summary-level GWAS · MVMR IVW
BETA 0.047 [-0.002, 0.096]
28498 participants
GRADE not reported