Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews · Breast Cancer

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 33.3%Moderate 0 · 0%High 2 · 66.7%

Local recurrence · breast‐conserving radiotherapy for breast cancer

Boost may leads to lower local control: recurrence at 5 years compared with no boost (low certainty).

1 finding from 1 review

Tumour bed boost radiotherapy for women after breast‐conserving surgery 2017 · Cochrane Headline outcomes only
HR 0.64 [0.55, 0.75]
5 studies · 8315 participants
Low

Sensitivity analysis: local control ‐ recurrence at 5 years · breast‐conserving radiotherapy for breast cancer

Boost leads to lower sensitivity analysis: local control ‐ recurrence at 5 years compared with no boost (high certainty).

1 finding from 1 review

Tumour bed boost radiotherapy for women after breast‐conserving surgery 2017 · Cochrane Headline outcomes only
HR 0.62 [0.52, 0.73]
3 studies · 6963 participants
High

Subgroup analysis: local control ‐ > 40 years old, recurrence at 5 years · breast‐conserving radiotherapy for breast cancer

Boost leads to lower subgroup analysis: local control ‐ > 40 years old, recurrence at 5… compared with no boost (high certainty).

1 finding from 1 review

Tumour bed boost radiotherapy for women after breast‐conserving surgery 2017 · Cochrane Headline outcomes only
HR 0.65 [0.53, 0.81]
2 studies · 5058 participants
High