Findings

What do systematic reviews say?

1 questions · 1 findings · 1 reviews · Musculoskeletal

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 1 · 100%High 0 · 0%

Paracetamol vs placebo

Liver toxicity: number experiencing abnormal liver function tests 24 weeks · Patients with osteoarthritis of the knee or hip

Paracetamol probably leads to higher liver toxicity: number experiencing abnormal liver function tests 24… compared with placebo (moderate certainty).

1 finding from 1 review

Paracetamol versus placebo for knee and hip osteoarthritis 2019 · Cochrane Headline outcomes only
RR 3.79 [1.94, 7.39]
3 studies · 1237 participants
Moderate