Findings

What do systematic reviews say?

5 questions · 5 findings · 3 reviews · Gynaecology and Fertility

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 20%Low 3 · 60%Moderate 1 · 20%High 0 · 0%

RhCG vs uhCG

Ongoing pregnancy / live birth rate per woman · patients with final oocyte maturation triggering in IVF and ICSI cycles

RhCG showed no clear difference in ongoing pregnancy/live birth rate per woman compared with uhCG (moderate certainty).

1 finding from 1 review

Recombinant versus urinary human chorionic gonadotrophin for final oocyte maturation triggering in IVF and ICSI cycles 2016 · Cochrane Headline outcomes only
OR 1.15 [0.89, 1.49]
7 studies · 1136 participants
Moderate

RhLH vs uhCG

Ongoing pregnancy / live birth rate per woman · patients with final oocyte maturation triggering in IVF and ICSI cycles

It is very uncertain whether rhLH changes ongoing pregnancy/live birth rate per woman compared with uhCG (very low certainty).

1 finding from 1 review

Recombinant versus urinary human chorionic gonadotrophin for final oocyte maturation triggering in IVF and ICSI cycles 2016 · Cochrane Headline outcomes only
OR 0.95 [0.51, 1.78]
2 studies · 289 participants
Very low

Modified natural cycle FET (HCG trigger) vs HT + GnRHa FET

Live birth rate per woman · subfertile women

Modified natural cycle FET (HCG trigger) showed no clear difference in live birth rate per woman compared with HT + GnRHa suppression FET (low certainty).

1 finding from 1 review

Cycle regimens for frozen‐thawed embryo transfer 2017 · Cochrane Headline outcomes only
OR 1.11 [0.66, 1.87]
1 study · 236 participants
Low

Natural cycle FET vs HT + GnRHa FET

Live birth rate per woman · subfertile women

Natural cycle FET showed no clear difference in live birth rate per woman compared with HT plus GnRHa suppression FET (low certainty).

1 finding from 1 review

Cycle regimens for frozen‐thawed embryo transfer 2017 · Cochrane Headline outcomes only
OR 0.77 [0.39, 1.53]
1 study · 159 participants
Low

GnRHa depot vs GnRHa daily injection

Ongoing pregnancy / live birth rate per woman · women undergoing pituitary suppression in assisted reproduction

GnRHa depot showed no clear difference in live birth/ongoing pregnancy rate per woman Delivery of one or more… compared with gnRHa daily injection (low certainty).

1 finding from 1 review

Depot versus daily administration of gonadotrophin‐releasing hormone agonist protocols for pituitary down regulation… 2013 · Cochrane Headline outcomes only
OR 0.95 [0.7, 1.31]
7 studies · 873 participants
Low