Gonadotrophins probably leads to higher live birth rate per woman compared with continued clomiphene citrate (moderate certainty).
Recombinant follicle stimulating hormone showed no clear difference in live birth rate per woman compared with urinary‐derived gonadotrophins (low certainty).
The review found no eligible studies for this question.
It is very uncertain whether human menopausal gonadotrophin or highly purified human menopausal… changes live birth rate per woman compared with urinary follicle stimulating hormone (very low certainty).
Metformin showed no clear difference in live birth rate per woman compared with placebo or no treatment (low certainty).
Metformin combined with clomiphene citrate showed no clear difference in live birth rate per woman compared with clomiphene citrate alone (low certainty).
Metformin may leads to higher live birth rate (per woman) compared with placebo co‐treatment (low certainty).
It is very uncertain whether metformin changes live birth rate per woman aParticipants with BMI ≥ 30 kg/m2 compared with clomiphene citrate (very low certainty).
It is very uncertain whether metformin changes live birth rate per woman aParticipants with BMI < 30 kg/m2 or ≤ 32… compared with clomiphene citrate (very low certainty).