Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

8 questions · 8 findings · 3 reviews

No studies found 0 · 0%GRADE not reported 1 · 12.5%Very low 2 · 25%Low 5 · 62.5%Moderate 0 · 0%High 0 · 0%

Progesterone vs no treatment or placebo (route of progesterone administration)

Live birth or ongoing pregnancy · women trying to conceive by intrauterine insemination

Progesterone showed no clear difference in live birth/ongoing pregnancy rate compared with no treatment or placebo (route of progesterone administration) (low certainty).

1 finding from 1 review

Summary of findings table ‐ Progestogens vs GnRH antagonists

Live birth or ongoing pregnancy sensitivity analysis ‐ PCOS (high‐responders) ‐ own oocytes ‐ early phase stimulation protocol ‐ frozen embryo transfer (micronised progesterone 100 mg/day versus GnRH antagonists) · assisted reproduction technology cycles

Summary of findings table ‐ Progestogens showed no clear difference in live birth or ongoing pregnancy sensitivity analysis ‐ PCOS… compared with gnRH antagonists; GRADE not reported.

1 finding from 1 review