Findings

What do systematic reviews say?

2 questions · 3 findings · 2 reviews · Gynaecology and Fertility

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 33.3%Moderate 2 · 66.7%High 0 · 0%

Progesterone vs no treatment or placebo (route of progesterone administration)

Live birth or ongoing pregnancy · women trying to conceive by intrauterine insemination

Progesterone showed no clear difference in live birth/ongoing pregnancy rate compared with no treatment or placebo (route of progesterone administration) (low certainty).

1 finding from 1 review

Luteal phase support for women trying to conceive by intrauterine insemination or sexual intercourse 2022 · Cochrane Headline outcomes only
RR 1.1 [0.81, 1.48]
7 studies · 1792 participants
Low

DHEA or testosterone vs placebo/no treatment

Live birth or ongoing pregnancy · women undergoing assisted reproduction

DHEA or testosterone probably leads to higher live birth/ongoing pregnancy rate ‐ DHEA compared with placebo/no treatment (moderate certainty).

2 findings from 1 review

Androgens (dehydroepiandrosterone or testosterone) for women undergoing assisted reproduction 2015 · Cochrane Headline outcomes only
OR 1.81 [1.25, 2.62]
8 studies · 878 participants
Moderate
Androgens (dehydroepiandrosterone or testosterone) for women undergoing assisted reproduction 2015 · Cochrane Headline outcomes only
OR 2.6 [1.3, 5.2]
4 studies · 345 participants
Moderate