What do systematic reviews say?

2 questions · 2 findings · 2 reviews · Pregnancy and Childbirth

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 1 · 50%High 1 · 50%

Intensity of glycaemic control for women with gestational diabetes mellitus ‐ strict glycaemic targets vs less‐tight glycaemic targets (child (as neonate, child, adult) outcomes)

Large‐for‐gestational age · Children (as neonate, child, adult) of women with GDM

Intensity of glycaemic control for women with gestational diabetes… showed no clear difference in large‐for‐gestational‐age compared with less‐tight glycaemic targets (child (as neonate, child, adult)… (moderate certainty).

1 finding from 1 review

Different intensities of glycaemic control for women with gestational diabetes mellitus 2023 · Cochrane Headline outcomes only
RR 0.96 [0.72, 1.29]
3 studies · 1556 participants
Moderate

Metformin vs placebo

Large‐for‐gestational age · women with obesity during pregnancy

Metformin showed no clear difference in large‐for‐gestational‐age infant, defined as birthweight ≥ 90th… compared with placebo (high certainty).

1 finding from 1 review

Metformin for women who are overweight or obese during pregnancy for improving maternal and infant outcomes 2018 · Cochrane Headline outcomes only
RR 0.95 [0.7, 1.3]
2 studies · 831 participants
High