Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Gynaecology and Fertility

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 4 · 57.1%Moderate 3 · 42.9%High 0 · 0%

Misoprostol vs osmotic dilator before operative hysteroscopy

Intraoperative complications · Pre and post menopausal women

Misoprostol showed no clear difference in intraoperative complications compared with osmotic dilator before operative hysteroscopy (low certainty).

1 finding from 1 review

Preoperative ripening of the cervix before operative hysteroscopy 2015 · Cochrane Headline outcomes only
OR 5.14 [0.24, 109.01]
3 studies · 354 participants
Low

Misoprostol vs placebo or no treatment before operative hysteroscopy

Intraoperative complications · Pre and post menopausal women

Misoprostol probably leads to lower intraoperative complications compared with placebo or no treatment before operative hysteroscopy (moderate certainty).

1 finding from 1 review

Preoperative ripening of the cervix before operative hysteroscopy 2015 · Cochrane Headline outcomes only
OR 0.37 [0.18, 0.77]
12 studies · 901 participants
Moderate

Misoprostol vs dinoprostone before operative hysteroscopy

Intraoperative complications · Pre and post menopausal women

Misoprostol may leads to lower intraoperative complications compared with dinoprostone before operative hysteroscopy (low certainty).

1 finding from 1 review

Preoperative ripening of the cervix before operative hysteroscopy 2015 · Cochrane Headline outcomes only
OR 0.32 [0.12, 0.83]
1 study · 310 participants
Low

Misoprostol vs placebo or no treatment before operative hysteroscopy

Specific intraoperative complications ‐ False track · Pre and post menopausal women

Misoprostol probably leads to lower specific intraoperative complications ‐ False track compared with placebo or no treatment before operative hysteroscopy (moderate certainty).

1 finding from 1 review

Preoperative ripening of the cervix before operative hysteroscopy 2015 · Cochrane Headline outcomes only
OR 0.34 [0.12, 0.97]
7 studies · 560 participants
Moderate

Misoprostol vs placebo or no treatment before operative hysteroscopy

Specific intraoperative complications ‐ Uterine bleeding · Pre and post menopausal women

Misoprostol showed no clear difference in specific intraoperative complications ‐ Uterine bleeding compared with placebo or no treatment before operative hysteroscopy (low certainty).

1 finding from 1 review

Preoperative ripening of the cervix before operative hysteroscopy 2015 · Cochrane Headline outcomes only
OR 0.51 [0.1, 2.49]
4 studies · 340 participants
Low

Misoprostol vs placebo or no treatment before operative hysteroscopy

Specific intraoperative complications ‐ Uterine perforation · Pre and post menopausal women

Misoprostol showed no clear difference in specific intraoperative complications ‐ Uterine perforation compared with placebo or no treatment before operative hysteroscopy (low certainty).

1 finding from 1 review

Preoperative ripening of the cervix before operative hysteroscopy 2015 · Cochrane Headline outcomes only
OR 0.42 [0.13, 1.38]
7 studies · 455 participants
Low

Misoprostol vs placebo or no treatment before operative hysteroscopy

Specific intraoperative complications ‐ Cervical laceration/tear · Pre and post menopausal women

Misoprostol probably leads to lower specific intraoperative complications ‐ Cervical laceration/tear compared with placebo or no treatment before operative hysteroscopy (moderate certainty).

1 finding from 1 review

Preoperative ripening of the cervix before operative hysteroscopy 2015 · Cochrane Headline outcomes only
OR 0.25 [0.11, 0.57]
9 studies · 669 participants
Moderate