Findings

What do systematic reviews say?

3 questions · 3 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 66.7%Moderate 1 · 33.3%High 0 · 0%

Low dialysate [Na+] (< 138 mM) vs neutral dialysate [Na+] (138 to 140 mM)

Intradialytic cramps · chronic HD

Low dialysate [Na+] (< 138 mM) showed no clear difference in intradialytic cramps compared with neutral dialysate [Na+] (138 to 140 mM) (low certainty).

1 finding from 1 review

Low dialysate sodium levels for chronic haemodialysis 2019 · Cochrane Headline outcomes only
RR 1.66 [0.92, 2.98]
4 studies · 11700 participants
Low

Low dialysate [Na+] (< 138 mM) vs neutral dialysate [Na+] (138 to 140 mM) or high dialysate [Na+] (> 140 mM)

Intradialytic cramps · chronic HD

Low dialysate [Na+] (< 138 mM) probably leads to higher intradialytic cramps compared with neutral dialysate [Na+] (138 to 140 mM) or high dialysate [Na+] (>… (moderate certainty).

1 finding from 1 review

Low dialysate sodium levels for chronic haemodialysis 2019 · Cochrane Headline outcomes only
RR 1.77 [1.15, 2.73]
6 studies · 12186 participants
Moderate

Low dialysate [Na+] (< 138 mM) vs high dialysate [Na+] (> 140 mM)

Intradialytic cramps · chronic HD

Low dialysate [Na+] (< 138 mM) may leads to higher intradialytic cramps compared with high dialysate [Na+] (> 140 mM) (low certainty).

1 finding from 1 review

Low dialysate sodium levels for chronic haemodialysis 2019 · Cochrane Headline outcomes only
RR 1.94 [1.54, 2.44]
2 studies · 486 participants
Low