Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 50%Low 1 · 50%Moderate 0 · 0%High 0 · 0%

Incidence of renal impairment · cardiac surgery for the treatment of non‐surgical bleeding

It is very uncertain whether PCC changes incidence of renal impairment compared with FVIIa (very low certainty).

1 finding from 1 review

Prothrombin complex concentrate in cardiac surgery for the treatment of coagulopathic bleeding 2022 · Cochrane Headline outcomes only
OR 0.29 [0.12, 0.71]
1 study · 106 participants
Very low

Incidence of renal impairment · cardiac surgery for the treatment of non‐surgical bleeding

PCC showed no clear difference in incidence of renal impairment compared with standard treatment (low certainty).

1 finding from 1 review