Findings

What do systematic reviews say?

2 questions · 2 findings · 1 reviews · Oral and maxillofacial surgery

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No studies found 0 · 0%GRADE not reported 1 · 50%Very low 1 · 50%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Delicate surgery and wound closure by primary intention vs Non-traumatic tooth avulsion and wound closure by secondary intention

MRONJ (incidence proportion) · People treated with oral bisphosphonates undergoing dental extractions (at risk of MRONJ)

1 finding from 1 review

Interventions for managing medication‐related osteonecrosis of the jaw 2022 · Cochrane All outcomes
In both study arms, no case of postoperative MRONJ was observed (700 participants; 1 RCT); effect not estimable.
1 study · 700 participants
GRADE not reported

Dental extraction protocol with plasma rich in growth factors (PRGF) inserted into the postextraction alveolus vs Standard dental extraction protocol without PRGF

MRONJ (incidence proportion) · People with cancer treated with intravenous bisphosphonates undergoing dental extractions (at risk of MRONJ)

It is very uncertain whether dental extraction protocol with plasma rich in growth factors (PRGF)… changes MRONJ (incidence proportion) compared with standard dental extraction protocol without PRGF (very low certainty).

1 finding from 1 review

Interventions for managing medication‐related osteonecrosis of the jaw 2022 · Cochrane All outcomes
24 to 60 months
RR 0.08 [0.00, 1.51]
1 study · 176 participants
Very low