Calcium minus Fluorine was -0.628 MPa (95% CI -8.504 to 7.248) at 24 h.
In the Self-Etch adhesive + chemical ACAD protocol network, HAp showed 4.455 MPa lower 24 h bond strength than Calcium Phosphate (MD -4.455, 95% CI -8.857 to -0.053; Moderate certainty).
In the Etch-and-Rinse adhesive + biological ACAD protocol network, Peptide showed 9.857 MPa higher 24 h bond strength than Flavonoids (MD 9.857, 95% CI 2.588 to 17.126; Moderate certainty).
In the Self-Etch adhesive + chemical ACAD protocol network, Silica vs Calcium Phosphate showed no significant difference in 24 h bond strength (MD -0.699, 95% CI -7.633 to 6.234; Moderate certainty).
In the Self-Etch adhesive + chemical ACAD protocol network, Calcium Phosphate vs Control showed no significant difference in 24 h bond strength (MD 1.539, 95% CI -1.738 to 4.817; Moderate certainty).
In the Self-Etch adhesive + chemical ACAD protocol network, HEMA vs Fluorine showed no significant difference in 24 h bond strength (MD 2.500, 95% CI -2.603 to 7.603; Low certainty).
In the Self-Etch adhesive + chemical ACAD protocol network, Flavonoids vs Calcium showed no significant difference in 24 h bond strength (MD 5.728, 95% CI -2.442 to 13.897; Moderate certainty).
In the Self-Etch adhesive + chemical ACAD protocol network, HAp showed 7.520 MPa lower 24 h bond strength than Flavonoids (MD -7.520, 95% CI -14.758 to -0.281; Moderate certainty).
In the Self-Etch adhesive + chemical ACAD protocol network, Silica vs HEMA showed no significant difference in 24 h bond strength (MD -1.059, 95% CI -9.024 to 6.906; Moderate certainty).
In the Self-Etch adhesive + chemical ACAD protocol network, Calcium vs Control showed no significant difference in 24 h bond strength (MD -1.124, 95% CI -5.917 to 3.670; Moderate certainty).
In the Self-Etch adhesive + chemical ACAD protocol network, Flavonoids vs Silica showed no significant difference in 24 h bond strength (MD 3.764, 95% CI -5.241 to 12.769; Moderate certainty).