Findings

What do systematic reviews say?

8 questions · 8 findings · 1 reviews · Eyes and Vision

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No studies found 2 · 25%GRADE not reported 0 · 0%Very low 2 · 25%Low 3 · 37.5%Moderate 1 · 12.5%High 0 · 0%

Medication vs placebo

IOP increase of ≥ 5 mmHg between 2 and 24 hours · people with glaucoma receiving LTP

Medication may leads to lower IOP increase of ≥ 5 mmHg between 2 and 24 hours compared with placebo (low certainty).

1 finding from 1 review

Perioperative medications for preventing temporarily increased intraocular pressure after laser trabeculoplasty 2017 · Cochrane Headline outcomes only
RR 0.17 [0.09, 0.31]
5 studies · 634 participants
Low

Medication vs placebo

IOP increase of ≥ 10 mmHg between 2 and 24 hours · people with glaucoma receiving LTP

It is very uncertain whether medication changes IOP increase of ≥ 10 mmHg between 2 and 24 hours compared with placebo (very low certainty).

1 finding from 1 review

Perioperative medications for preventing temporarily increased intraocular pressure after laser trabeculoplasty 2017 · Cochrane Headline outcomes only
RR 0.22 [0.11, 0.42]
9 studies · 817 participants
Very low

Medication given before LTP vs the same medication given after LTP

IOP increase of ≥ 5 mmHg between 2 and 24 hours · people with glaucoma receiving LTP

Medication given before LTP showed no clear difference in IOP increase of ≥ 5 mmHg between 2 and 24 hours compared with the same medication given after LTP (moderate certainty).

1 finding from 1 review

Perioperative medications for preventing temporarily increased intraocular pressure after laser trabeculoplasty 2017 · Cochrane Headline outcomes only
RR 0.82 [0.25, 2.63]
4 studies · 319 participants
Moderate

Medication given before LTP vs the same medication given after LTP

IOP increase of ≥ 10 mmHg between 2 and 24 hours · people with glaucoma receiving LTP

It is very uncertain whether medication given before LTP changes IOP increase of ≥ 10 mmHg between 2 and 24 hours compared with the same medication given after LTP (very low certainty).

1 finding from 1 review

Perioperative medications for preventing temporarily increased intraocular pressure after laser trabeculoplasty 2017 · Cochrane Headline outcomes only
RR 1.55 [0.19, 12.43]
4 studies · 319 participants
Very low

Brimonidine vs apraclonidine

IOP increase of ≥ 5 mmHg between 2 and 24 hours · people with glaucoma receiving LTP

The review found no eligible studies for this question.

1 finding from 1 review

Perioperative medications for preventing temporarily increased intraocular pressure after laser trabeculoplasty 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Apraclonidine vs pilocarpine

IOP increase of ≥ 5 mmHg between 2 and 24 hours · people with glaucoma receiving LTP

1 finding from 1 review

Perioperative medications for preventing temporarily increased intraocular pressure after laser trabeculoplasty 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
Low

Brimonidine vs apraclonidine

IOP increase of ≥ 10 mmHg between 2 and 24 hours · people with glaucoma receiving LTP

The review found no eligible studies for this question.

1 finding from 1 review

Perioperative medications for preventing temporarily increased intraocular pressure after laser trabeculoplasty 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Apraclonidine vs pilocarpine

IOP increase of ≥ 10 mmHg between 2 and 24 hours · people with glaucoma receiving LTP

Apraclonidine showed no clear difference in IOP increase of ≥ 10 mmHg between 2 and 24 hours compared with pilocarpine (low certainty).

1 finding from 1 review

Perioperative medications for preventing temporarily increased intraocular pressure after laser trabeculoplasty 2017 · Cochrane Headline outcomes only
RR 0.87 [0.14, 5.63]
2 studies · 390 participants
Low