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What do systematic reviews say?

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Evidence found and GRADE certainty

2 questions · 2 findings · 2 reviews · Emergency and Critical Care

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 50%Moderate 1 · 50%High 0 · 0%

Protocol‐directed sedation management vs usual care

ICU mortality · mechanically ventilated ICU adults and children requiring sedation management

Protocol‐directed sedation management showed no clear difference in ICU mortality compared with usual care (low certainty).

1 finding from 1 review

Daily sedation interruption vs usual care or protocolized sedation strategies that do not include daily sedation interruption

ICU mortality · Critically ill adults receiving mechanical ventilation in ICU

Daily sedation interruption showed no clear difference in ICU mortality compared with usual care or protocolized sedation strategies that do not include… (moderate certainty).

1 finding from 1 review