Findings

What do systematic reviews say?

4 questions · 4 findings · 3 reviews · Headline outcomes only

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No studies found 1 · 25%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 25%Moderate 2 · 50%High 0 · 0%

Summary of findings: intranasal steroids plus oral antibiotic vs control plus antibiotic

Hearing loss · Children with otitis media with effusion

The review found no eligible studies for this question.

1 finding from 1 review

Oral or topical nasal steroids for hearing loss associated with otitis media with effusion in children 2011 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Gastrointestinal adverse events in people taking macrolide antibiotics vs placebo

Hearing loss · any indication

Other adverse events in people taking macrolide antibiotics showed no clear difference in hearing loss compared with placebo (low certainty).

1 finding from 1 review

Adverse events in people taking macrolide antibiotics versus placebo for any indication 2019 · Cochrane Headline outcomes only
OR 1.3 [1, 1.7]
4 studies · 1369 participants
Low

Summary of findings: oral steroids plus antibiotic vs control plus antibiotic

Hearing loss · Children with otitis media with effusion

Summary of findings: oral steroids plus antibiotic showed no clear difference in hearing loss [2 months]1 compared with control plus antibiotic (moderate certainty).

1 finding from 1 review

Oral or topical nasal steroids for hearing loss associated with otitis media with effusion in children 2011 · Cochrane Headline outcomes only
RR 1.01 [0.73, 1.4]
1 study · 99 participants
Moderate

Intervention not reported

Hearing loss · children and adults with acute bacterial meningitis

The intervention probably leads to lower hearing loss (moderate certainty).

1 finding from 1 review

Osmotic therapies added to antibiotics for acute bacterial meningitis 2018 · Cochrane Headline outcomes only
RR 0.64 [0.44, 0.93]
5 studies · 922 participants
Moderate