Antibiotics vs no treatment or placebo on top of topical antibiotics
Hearing · people (of any age) with CSOM
The review found no eligible studies for this question.
1 finding from 1 review
- no estimate extractedStudies not reportedNo studies found
Findings
What do systematic reviews say?
13 questions · 13 findings · 7 reviews · ENT
No studies found 1 · 7.7%GRADE not reported 0 · 0%Very low 7 · 53.8%Low 3 · 23.1%Moderate 2 · 15.4%High 0 · 0%
Antibiotics vs no treatment/placebo
Hearing · children with CSOM
1 finding from 1 review
- no estimate extracted1 study · 33 participantsVery low
Topical antibiotics vs placebo/no treatment
Hearing · patients with mucopurulent otorrhoea
1 finding from 1 review
- no estimate extracted1 study · 35 participantsVery low
Topical antibiotics with steroids vs placebo/no treatment
Hearing · chronic suppurative otitis media
1 finding from 1 review
- Topical antibiotics with steroids for chronic suppurative otitis media 2020 · Cochrane Headline outcomes onlyno estimate extracted1 study · 123 participantsVery low
Antibiotics vs no treatment or placebo on top of topical antibiotics
Hearing ‐ unclear · people with CSOM; one study included patients of unknown age; one study included children with CSOM who had not responded to initial…
1 finding from 1 review
- no estimate extracted1 study · 38 participantsVery low
Oral steroids vs placebo
Hearing ‐ return to normal *Ventilation tubes versus laser myringotomy (6 to 12 months ‐ medium‐term) Adjusted for non‐independence of within‐individual measurements Assumed ICC of 0.5 № of participants: 132 (2 RCTs) · children aged 6 months to 12 years with otitis media with effusion (OME)
Oral steroids showed no clear difference in hearing ‐ return to normal hearing compared with placebo (moderate certainty).
1 finding from 1 review
- Topical and oral steroids for otitis media with effusion (OME) in children 2023 · Cochrane Headline outcomes onlyRR 1.14 [0.97, 1.33]Studies not reportedModerate
Antibiotics vs no treatment or placebo on top of topical antiseptics
Hearing · schoolchildren with CSOM
1 finding from 1 review
- no estimate extracted1 study · 204 participantsVery low
Positive pressure therapy vs placebo
Loss or gain of hearing in 4 months (dB) · Ménière’s disease
1 finding from 1 review
- no estimate extracted2 studies · 123 participantsModerate
Intranasal steroid spray vs placebo
Hearing · children aged 6 months to 12 years with otitis media with effusion (OME)
1 finding from 1 review
- Topical and oral steroids for otitis media with effusion (OME) in children 2023 · Cochrane Headline outcomes onlyno estimate extractedStudies not reportedVery low
Intratympanic corticosteroids vs no treatment or versus placebo
Proportion of patients whose hearing is improved · sudden sensorineural hearing loss
Intratympanic corticosteroids may leads to higher proportion of patients whose hearing is improved compared with no treatment or versus placebo (low certainty).
1 finding from 1 review
- Intratympanic corticosteroids for sudden sensorineural hearing loss 2022 · Cochrane Headline outcomes onlyRR 5.55 [2.89, 10.68]6 studies · 232 participantsLow
Intratympanic corticosteroids vs no treatment or versus placebo
Final hearing threshold determined by PTA (a lower value represents better hearing) · sudden sensorineural hearing loss
Intratympanic corticosteroids showed no clear difference in final hearing threshold determined by PTA (a lower value represents… compared with no treatment or versus placebo (low certainty).
1 finding from 1 review
- Intratympanic corticosteroids for sudden sensorineural hearing loss 2022 · Cochrane Headline outcomes onlyno estimate extracted5 studies · 203 participantsLow
Antibiotics vs placebo
Hearing ‐ return to normal *Ventilation tubes versus laser myringotomy (6 to 12 months ‐ medium‐term) Adjusted for non‐independence of within‐individual measurements Assumed ICC of 0.5 № of participants: 132 (2 RCTs) · children aged 6 months to 12 years with otitis media with effusion (OME)
It is very uncertain whether antibiotics changes hearing ‐ return to normal hearing (as complete improvement in… compared with placebo (very low certainty).
1 finding from 1 review
- Peto OR 9.59 [3.51, 26.18]Studies not reportedVery low
Intratympanic corticosteroids vs no treatment or versus placebo
Change in hearing threshold determined by PTA Range 0 dB to 140 dB Negative values represent lowering and positive values represent raising of the hearing threshold. A lower hearing threshold represents hearing improvement. Â · sudden sensorineural hearing loss
Intratympanic corticosteroids showed no clear difference in change in hearing threshold determined by PTA Range 0 dB to 140 dB… compared with no treatment or versus placebo (low certainty).
1 finding from 1 review
- Intratympanic corticosteroids for sudden sensorineural hearing loss 2022 · Cochrane Headline outcomes onlyno estimate extracted7 studies · 280 participantsLow