What do systematic reviews say?

Complex information, support and training interventions vs inactive control (usual care care, attention control, waitlist)

• Remotely delivered information, training and support for informal caregivers of people with dementia 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 311 participants
  Moderate

Complex information, support and training interventions vs information only

• Remotely delivered information, training and support for informal caregivers of people with dementia 2021 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 257 participants
  Low

Self‐management interventions vs usual care

• Self‐management interventions including action plans for exacerbations versus usual care in patients with chronic… 2017 · Cochrane Headline outcomes only
  no estimate extracted
  10 studies · 1582 participants
  High

Summary of findings for the main comparison. Physical activity and exercise interventions vs usual care

• Physical activity interventions for people with congenital heart disease 2020 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 163 participants
  Very low

Parent‐only interventions vs minimal contact control

• Parent‐only interventions for childhood overweight or obesity in children aged 5 to 11 years 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 93 participants
  GRADE not reported

Information or education intervention vs no education

• Information or education interventions for adult intensive care unit (ICU) patients and their carers 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 143 participants
  Very low

Metformin 500 mg to 2550 mg per day vs placebo

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Relaxation vs usual care

The review found no eligible studies for this question.

• Psychosocial interventions for preventing and treating depression in dialysis patients 2019 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

CBT vs usual care

Cognitive‐behavioural therapy probably leads to higher health‐related quality of life Investigators measured health‐related… compared with usual care (moderate certainty).

• Psychosocial interventions for preventing and treating depression in dialysis patients 2019 · Cochrane Headline outcomes only
  SMD 0.51 [0.19, 0.83]
  4 studies · 230 participants
  Moderate

Flutamide 250 mg once to b.i.d. vs metformin 1275 mg to 1700 mg per day

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Physical activity vs usual care

• Physical activity interventions for disease‐related physical and mental health during and following treatment in… 2020 · Cochrane Headline outcomes only
  no estimate extracted
  6 studies · 230 participants
  Moderate

Smart technology vs face‐to‐face/digital and/or written support

• Computer and mobile technology interventions for self‐management in chronic obstructive pulmonary disease 2017 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 472 participants
  Low

Flutamide 250 mg once to b.i.d. vs spironolactone 100 mg

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Ethinyl estradiol 35 μg + cyproterone acetate 2 mg vs ethinyl estradiol 30 μg + desogestrel 0.15 mg

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Spironolactone 100 mg vs placebo

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Finasteride 5 mg to 7.5 mg vs placebo

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Finasteride 5 mg vs spironolactone 100 mg

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Finasteride 5 mg vs flutamide 250 mg once to b.i.d.

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Flutamide 250 mg b.i.d. vs placebo

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Surgical vs non‐surgical treatment

• Surgical versus non‐surgical interventions for displaced intra‐articular calcaneal fractures 2023 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 192 participants
  Low