What do systematic reviews say?

Serlopitant 0.25 mg vs placebo

• Interventions for chronic pruritus of unknown origin 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 127 participants
  Very low

Serlopitant 5 mg vs placebo

• Interventions for chronic pruritus of unknown origin 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 127 participants
  Very low

Serlopitant 1 mg vs placebo

• Interventions for chronic pruritus of unknown origin 2020 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 128 participants
  Very low

Summary of findings table ‐ Oral classical immunosuppressants (prednisolone or cyclosporine) vs placebo

• Treatments for alopecia areata: a network meta‐analysis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 36 participants
  Very low

Summary of findings table ‐ Intralesional classical immunosuppresants (betamethasone or triamcinolone) vs placebo

The review found no eligible studies for this question.

• Treatments for alopecia areata: a network meta‐analysis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings table ‐ Subcutaneous biologics (dupilumab) vs placebo

The review found no eligible studies for this question.

• Treatments for alopecia areata: a network meta‐analysis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings table ‐ Oral small molecule inhibitors (apremilast or baricitinib) vs placebo

The review found no eligible studies for this question.

• Treatments for alopecia areata: a network meta‐analysis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings table ‐ Topical small molecule inhibitors (ruxolitinib) vs placebo

The review found no eligible studies for this question.

• Treatments for alopecia areata: a network meta‐analysis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Summary of findings table ‐ Contact immunotherapy (diphencyprone or squaric acid dibutil ester) vs placebo

The review found no eligible studies for this question.

• Treatments for alopecia areata: a network meta‐analysis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Minoxidil vs placebo

The review found no eligible studies for this question.

• Treatments for alopecia areata: a network meta‐analysis 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

NB‐UVB vs placebo

The review found no eligible studies for this question.

• Phototherapy for atopic eczema 2021 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Moisturisers vs vehicle, placebo or no moisturiser

• Emollients and moisturisers for eczema 2017 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 300 participants
  Low

Spironolactone 100 mg vs placebo

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Finasteride 5 mg to 7.5 mg vs placebo

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Metformin 500 mg to 2550 mg per day vs placebo

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Flutamide 250 mg b.i.d. vs placebo

The review found no eligible studies for this question.

• Interventions for hirsutism (excluding laser and photoepilation therapy alone) 2015 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Urea‐containing moisturisers vs vehicle, placebo or no moisturiser

The review found no eligible studies for this question.

• Emollients and moisturisers for eczema 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Glycerin/glycerol‐containing moisturisers vs vehicle or placebo

The review found no eligible studies for this question.

• Emollients and moisturisers for eczema 2017 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Etanercept vs placebo

• Anti‐TNF agents for paediatric psoriasis 2015 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 211 participants
  Moderate