Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

130 questions · 130 findings · 56 reviews

No studies found 75 · 57.7%GRADE not reported 3 · 2.3%Very low 12 · 9.2%Low 27 · 20.8%Moderate 10 · 7.7%High 3 · 2.3%

Next‐generation ALK inhibitor vs crizotinib

Health‐related quality of life: time to deterioration in composite endpoint (cough, dyspnoea, and chest pain) · advanced anaplastic lymphoma kinase (ALK)‐rearranged non‐small cell lung cancer

It is very uncertain whether next‐generation ALK inhibitor changes health‐related quality of life: time to deterioration in composite… compared with crizotinib (very low certainty).

1 finding from 1 review

Intervention not reported

Health‐related quality of life a. Intervention vs thiazolidinediones [12 months] b. Intervention vs insulin [6 years] c. Intervention vs alpha‐glucosidase inhibitors [12 months] · participants with type 2 diabetes mellitus
1 finding from 1 review