Hyperbaric oxygen therapy plus standard care (surgery, antibiotics, oral rinse) vs Standard care alone (surgery, antibiotics, oral rinse)
Healing of osteonecrosis - improvement ('healed' or 'improved' vs 'unchanged' or 'worse') · People with BRONJ (mean age ~66 years; most treated with bisphosphonates for cancer (multiple myeloma, breast cancer) or osteoporosis)
Hyperbaric oxygen therapy plus standard care (surgery, antibiotics,… showed no clear difference in healing of osteonecrosis - improvement ('healed' or 'improved' vs… compared with standard care alone (surgery, antibiotics, oral rinse); GRADE not reported.
5 findings from 1 review
- Interventions for treating bisphosphonate‐related osteonecrosis of the jaw (BRONJ) 2016 · Cochrane All outcomes18 monthsRR 1.75 [0.51, 5.98]1 study · 18 participantsGRADE not reported
- Interventions for treating bisphosphonate‐related osteonecrosis of the jaw (BRONJ) 2016 · Cochrane All outcomesLast contactRR 1.78 [0.97, 3.28]1 study · 46 participantsGRADE not reported
- Interventions for treating bisphosphonate‐related osteonecrosis of the jaw (BRONJ) 2016 · Cochrane All outcomes3 monthsRR 1.94 [1.01, 3.74]1 study · 45 participantsVery low
Show 2 more findings
- Interventions for treating bisphosphonate‐related osteonecrosis of the jaw (BRONJ) 2016 · Cochrane All outcomes6 monthsRR 1.31 [0.78, 2.22]1 study · 40 participantsGRADE not reported
- Interventions for treating bisphosphonate‐related osteonecrosis of the jaw (BRONJ) 2016 · Cochrane All outcomes12 monthsRR 1.65 [0.75, 3.64]1 study · 24 participantsGRADE not reported