Findings

What do systematic reviews say?

9 questions · 15 findings · 5 reviews

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No studies found 4 · 26.7%GRADE not reported 0 · 0%Very low 5 · 33.3%Low 0 · 0%Moderate 6 · 40%High 0 · 0%

Botulinum toxin vs observation

Improvement in functional ability · people with sixth nerve palsy

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for eye movement disorders due to acquired brain injury 2018 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Botulinum toxin type A vs placebo

Sexual dysfunction ‐ not reported · participants with chronic prostatitis/chronic pelvic pain syndrome

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for treating chronic prostatitis/chronic pelvic pain syndrome 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Botulinum toxin A (with and without casting) vs placebo (with and without casting)

Sensory functions and pain · adults with traumatic brain injury with spasticity in their arms (1 study) or calves (1 study)

The review found no eligible studies for this question.

1 finding from 1 review

Interventions for managing skeletal muscle spasticity following traumatic brain injury 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Botulinum toxin A (with and without casting) vs placebo (with and without casting)

Neuromusculoskeletal and movement‐related functions at 12 weeks (measured by ankle dorsiflexion) · adults with traumatic brain injury with spasticity in their arms (1 study) or calves (1 study)

1 finding from 1 review

Interventions for managing skeletal muscle spasticity following traumatic brain injury 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 47 participants
Very low

BoNT‐A vs usual care or physiotherapy

Function · children with CP

3 findings from 1 review

Botulinum toxin type A in the treatment of lower limb spasticity in children with cerebral palsy 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 191 participants
Very low
Botulinum toxin type A in the treatment of lower limb spasticity in children with cerebral palsy 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 199 participants
Very low
Botulinum toxin type A in the treatment of lower limb spasticity in children with cerebral palsy 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 123 participants
Very low

BoNT‐A vs sham

Function · children with CP

3 findings from 1 review

Botulinum toxin type A in the treatment of lower limb spasticity in children with cerebral palsy 2019 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 305 participants
Moderate
Botulinum toxin type A in the treatment of lower limb spasticity in children with cerebral palsy 2019 · Cochrane Headline outcomes only
no estimate extracted
5 studies · 327 participants
Moderate
Botulinum toxin type A in the treatment of lower limb spasticity in children with cerebral palsy 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 91 participants
Moderate

BoNT‐A vs serial casting

Function · children with CP

3 findings from 1 review

Botulinum toxin type A in the treatment of lower limb spasticity in children with cerebral palsy 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 18 participants
Moderate
Botulinum toxin type A in the treatment of lower limb spasticity in children with cerebral palsy 2019 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 41 participants
Moderate
Botulinum toxin type A in the treatment of lower limb spasticity in children with cerebral palsy 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 18 participants
Moderate

BoNT‐A vs orthoses

Function · children with CP

1 finding from 1 review

Botulinum toxin type A in the treatment of lower limb spasticity in children with cerebral palsy 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 43 participants
Very low

Intervention not reported

Disability/function ‐ not reported · patients with shoulder pain

The review found no eligible studies for this question.

1 finding from 1 review

Botulinum toxin for shoulder pain 2010 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found