Findings

What do systematic reviews say?

4 questions · 7 findings · 1 reviews · Oral and maxillofacial surgery

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No studies found 0 · 0%GRADE not reported 7 · 100%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

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The findings closest to your search, judged one by one by TypeSafe's Jev model.

Direct match · question page
- Genetically predicted DMFS (dental caries) vs Lower genetically predicted DMFS · Forearm fracture
  From teeth to bone: dental caries has causal effects on osteoporosis and osteoporotic fracture. 2025 All outcomes
  Summary-level GWAS · SVMR Weighted Median
  OR 0.914 [0.799, 1.046]
  490889 participants
  GRADE not reported
Direct match · question page
- Genetically predicted dental caries (DMFS index) vs Reference (1-SD lower genetically predicted DMFS) · Fracture of forearm
  From teeth to bone: dental caries has causal effects on osteoporosis and osteoporotic fracture. 2025 All outcomes
  Lifelong genetic liability · European-ancestry population (two-sample MR: GLIDE exposures; FinnGen osteoporosis/fractures; GeFOS BMD) · MVMR (IVW), adjusted for periodontitis
  OR 0.973 [0.891, 1.063]
  490889 participants
  GRADE not reported
Direct match · question page
- Genetically predicted DMFS (dental caries) vs Lower genetically predicted DMFS, adjusted for periodontitis · Forearm fracture
  From teeth to bone: dental caries has causal effects on osteoporosis and osteoporotic fracture. 2025 All outcomes
  Summary-level GWAS · MVMR MR-Egger
  OR 0.901 [0.751, 1.081]
  490889 participants
  GRADE not reported
Related · question page
- Genetically predicted periodontitis vs Lower genetically predicted periodontitis liability, adjusted for DMFS · Forearm fracture
  From teeth to bone: dental caries has causal effects on osteoporosis and osteoporotic fracture. 2025 All outcomes
  Summary-level GWAS · MVMR MR-Egger
  OR 0.992 [0.950, 1.036]
  490889 participants
  GRADE not reported

Genetically predicted DMFS (dental caries) vs Lower genetically predicted DMFS, adjusted for periodontitis

Forearm fracture · European GWAS participants

The MVMR MR-Egger interval included the null.

1 finding from 1 review

From teeth to bone: dental caries has causal effects on osteoporosis and osteoporotic fracture. 2025 All outcomes
Summary-level GWAS · MVMR MR-Egger
OR 0.901 [0.751, 1.081]
490889 participants
GRADE not reported

Genetically predicted DMFS (dental caries) vs Lower genetically predicted DMFS

Forearm fracture · European GWAS participants

The SVMR Weighted Median interval included the null.

3 findings from 1 review

From teeth to bone: dental caries has causal effects on osteoporosis and osteoporotic fracture. 2025 All outcomes
Summary-level GWAS · SVMR Weighted Median
OR 0.914 [0.799, 1.046]
490889 participants
GRADE not reported
From teeth to bone: dental caries has causal effects on osteoporosis and osteoporotic fracture. 2025 All outcomes
Summary-level GWAS · SVMR MR-Egger
OR 0.883 [0.738, 1.057]
490889 participants
GRADE not reported
From teeth to bone: dental caries has causal effects on osteoporosis and osteoporotic fracture. 2025 All outcomes
Summary-level GWAS · SVMR Maximum Likelihood
OR 0.920 [0.836, 1.011]
490889 participants
GRADE not reported

Genetically predicted DMFS (dental caries) vs Reference (1-SD lower genetically predicted DMFS)

Forearm fracture · European-ancestry adults

Genetically predicted dental caries (DMFS) had no significant causal effect on fracture of forearm (multivariable MR, OR 0.973).

2 findings from 1 review

From teeth to bone: dental caries has causal effects on osteoporosis and osteoporotic fracture. 2025 All outcomes
Lifelong genetic liability · European-ancestry population (two-sample MR: GLIDE exposures; FinnGen osteoporosis/fractures; GeFOS BMD) · MVMR (IVW), adjusted for periodontitis
OR 0.973 [0.891, 1.063]
490889 participants
GRADE not reported
From teeth to bone: dental caries has causal effects on osteoporosis and osteoporotic fracture. 2025 All outcomes
Lifelong genetic liability · European-ancestry population (two-sample MR: GLIDE exposures; FinnGen osteoporosis/fractures; GeFOS BMD) · SVMR (IVW), total causal effect
OR 0.921 [0.838, 1.012]
490889 participants
GRADE not reported

Genetically predicted periodontitis vs Lower genetically predicted periodontitis liability, adjusted for DMFS

Forearm fracture · European GWAS participants

The MVMR MR-Egger interval included the null.

1 finding from 1 review

From teeth to bone: dental caries has causal effects on osteoporosis and osteoporotic fracture. 2025 All outcomes
Summary-level GWAS · MVMR MR-Egger
OR 0.992 [0.950, 1.036]
490889 participants
GRADE not reported