Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 3 · 75%Low 1 · 25%Moderate 0 · 0%High 0 · 0%

Standard‐dose adrenaline (SDA) vs SDA plus vasopressin

Favourable neurological outcomes · people suffering cardiac arrest

It is very uncertain whether standard‐dose adrenaline (SDA) changes favourable neurological outcomes compared with SDA plus vasopressin (very low certainty).

1 finding from 1 review

Adrenaline and vasopressin for cardiac arrest 2019 · Cochrane Headline outcomes only
RR 0.65 [0.33, 1.31]
1 study · 2887 participants
Very low

Standard‐dose adrenaline (SDA) vs high‐dose adrenaline (HDA)

Favourable neurological outcomes · people suffering cardiac arrest

It is very uncertain whether standard‐dose adrenaline (SDA) changes favourable neurological outcomes compared with high‐dose adrenaline (HDA) (very low certainty).

1 finding from 1 review

Adrenaline and vasopressin for cardiac arrest 2019 · Cochrane Headline outcomes only
RR 0.91 [0.65, 1.26]
4 studies · 5803 participants
Very low

Standard‐dose adrenaline (SDA) vs vasopressin

Favourable neurological outcomes · people suffering cardiac arrest

It is very uncertain whether standard‐dose adrenaline (SDA) changes favourable neurological outcomes compared with vasopressin (very low certainty).

1 finding from 1 review

Adrenaline and vasopressin for cardiac arrest 2019 · Cochrane Headline outcomes only
RR 0.82 [0.54, 1.25]
4 studies · 2406 participants
Very low

Standard‐dose adrenaline (SDA) vs placebo

Favourable neurological outcomes · people suffering cardiac arrest

Standard‐dose adrenaline (SDA) showed no clear difference in favourable neurological outcomes compared with placebo (low certainty).

1 finding from 1 review

Adrenaline and vasopressin for cardiac arrest 2019 · Cochrane Headline outcomes only
RR 1.21 [0.9, 1.62]
2 studies · 8535 participants
Low