Findings

What do systematic reviews say?

1 questions · 1 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 100%Moderate 0 · 0%High 0 · 0%

Briakinumab vs placebo

Failure to induce clinical remission at end of study · induction of remission in Crohn's disease

Briakinumab showed no clear difference in failure to induce clinical remission (Mannon 2004) CDAI (≤150 points) compared with placebo (low certainty).

1 finding from 1 review

Anti‐IL‐12/23p40 antibodies for induction of remission in Crohn's disease 2016 · Cochrane Headline outcomes only
RR 0.86 [0.65, 1.14]
1 study · 79 participants
Low